{"product_id":"nsj-rq8020-100ug","title":"PPP1R15B Antibody \/ Protein phosphatase 1 regulatory subunit 15B, 100 ug","description":"\u003cp\u003ePPP1R15B (Protein phosphatase 1, regulatory subunit 15b), also called CREP, promotes dephosphorylation of the transcription initiation factor EIF2-alpha through recruitment of protein phosphatase-1(PP1) catalytic subunits. The PPP1R15B gene is mapped to chromosome 1q32.1 based on an alignment of thePPP1R15B sequence by Hartz(2010). Harding et al.(2009) obtained Ppp1r15b -\/- mice at a mendelian ratio. However, Ppp1r15b -\/- newborns were half the size of their wildtype littermates, were notably pale, and failed to nurse, and none survived the first day of postnatal life. Ppp1r15b -\/- embryos that were also homozygous for an Eif2-alpha mutation that prevented Eif2-alpha phosphorylation were normalized, including elevated birth size and restored red blood cell count, compared with Ppp1r15b -\/- embryos with wildtype Eif2-alpha.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":48536116429024,"sku":"RQ8020","price":449.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/files\/get_image_53022fba-fe03-4d6c-beff-7530b756be4b.jpg?v=1768301964","url":"https:\/\/rndmate.com\/products\/nsj-rq8020-100ug","provider":"알앤디메이트","version":"1.0","type":"link"}