{"product_id":"nsj-v2588ihc-7ml","title":"HLA-DRB1 Antibody (MHC II), 7 ml","description":"\u003cp\u003eThis mAb reacts with a 28kDa chain of HLA-DRB1 antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes\/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3\/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts. Loss of HLA-DR expression is related to tumor microenvironment and predicts adverse outcome in diffuse large B-cell lymphoma.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"7 ml","offer_id":48535168876768,"sku":"V2588IHC-7ML","price":559.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/files\/get_image_d4c0e80b-661d-4e52-a863-897e060921f9.jpg?v=1768291226","url":"https:\/\/rndmate.com\/products\/nsj-v2588ihc-7ml","provider":"알앤디메이트","version":"1.0","type":"link"}