{"product_id":"nsj-v3029saf-100ug","title":"LAMP-3 Antibody \/ CD63, 100 ug","description":"\u003cp\u003eThis mAb recognizes protein of 26kDa-60kDa, which is identified as CD63\/LAMP-3. Its epitope is different from that of mAb LAMP3\/529. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63\/LAMP-3 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. It is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63\/LAMP-3 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. Deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":48535061332192,"sku":"V3029SAF-100UG","price":559.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/files\/get_image_18a4c435-8d5c-4189-9a86-f61fc13df90f.jpg?v=1768289453","url":"https:\/\/rndmate.com\/products\/nsj-v3029saf-100ug","provider":"알앤디메이트","version":"1.0","type":"link"}