{"product_id":"nsj-v3204-100ug","title":"Plakoglobin Antibody \/ Gamma Catenin, 100 ug","description":"\u003cp\u003eIt recognizes a protein of 80-87kDa, identified as gamma-Catenin or Plakoglobin. The catenins (Î±, Î², Î³ and Î´) are ubiquitously expressed, cytoplasmic proteins that associate with E-cadherin at cellular junctions. Catenin\/cadherin complexes play an important role in mediating cellular adhesion. Î± T-catenin, also referred to as VR22, is a 895-amino acid protein that is most abundantly expressed in cardio-myocytes and in the peritubular myoid cells of the testis. Î± T-catenin binds to Î± E-catenin as well as to Î²-catenin, and it functions to inhibit Wnt signaling. CTNNA3, the gene that encodes for Î±-T-catenin, is located on chromosome 10, and mutations in this gene show a strong correlation to late-onset Alzheimer s disease (LOAD) as well as to dilated cardiomyopathy.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":48535033708768,"sku":"V3204-100UG","price":559.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/files\/get_image_1fd2d8ea-2531-4f79-808f-ecf41048d1e5.jpg?v=1768288787","url":"https:\/\/rndmate.com\/products\/nsj-v3204-100ug","provider":"알앤디메이트","version":"1.0","type":"link"}