{"product_id":"nsj-v3204-20ug","title":"Plakoglobin Antibody \/ Gamma Catenin, 20 ug","description":"\u003cp\u003eIt recognizes a protein of 80-87kDa, identified as gamma-Catenin or Plakoglobin. The catenins (Î±, Î², Î³ and Î´) are ubiquitously expressed, cytoplasmic proteins that associate with E-cadherin at cellular junctions. Catenin\/cadherin complexes play an important role in mediating cellular adhesion. Î± T-catenin, also referred to as VR22, is a 895-amino acid protein that is most abundantly expressed in cardio-myocytes and in the peritubular myoid cells of the testis. Î± T-catenin binds to Î± E-catenin as well as to Î²-catenin, and it functions to inhibit Wnt signaling. CTNNA3, the gene that encodes for Î±-T-catenin, is located on chromosome 10, and mutations in this gene show a strong correlation to late-onset Alzheimer s disease (LOAD) as well as to dilated cardiomyopathy.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"20 ug","offer_id":48535033643232,"sku":"V3204-20UG","price":259.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/files\/get_image_09fd4834-b349-4197-a81e-ed4a53e22678.jpg?v=1768288785","url":"https:\/\/rndmate.com\/products\/nsj-v3204-20ug","provider":"알앤디메이트","version":"1.0","type":"link"}