{"product_id":"nsj-v5664-20ug","title":"Clusterin Antibody \/ CLU \/ APO-J, 20 ug","description":"\u003cp\u003eClusterin, also designated complement lysis inhibitor (CLI), apolipoprotein J (APOJ), sulfated glycoprotein 2 (SGP2), SP40 and testosterone-repressed prostate message 2 (TRPM2), is a secretory, heterodimeric glycoprotein that influences immune regulation, cell adhesion, transformation, lipid transportation, tissue remodeling, membrane recycling and cell-cell interactions. Clusterin is synthesized as a 449 amino acid polypeptide that is post-translationally cleaved at an internal bond between Arg 227 and Ser 228. Two subunits, 伪 and å°¾, are associated through disulfide bonds. The å°¾ subunit (also called ApoJ伪) corresponds to residues 23-227. The 伪 subunit (also called ApoJå°¾) corresponds to residues 228-449. Overexpression of Clusterin appears to be more common in late stages of mammary tumor progression. Clusterin markedly influences å°¾-Amyloid structure and neuritic toxicity in vivo and may influence Alzheimer s pathogenesis.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"20 ug","offer_id":48534432415968,"sku":"V5664-20UG","price":259.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/files\/get_image_aa644f7b-90d1-49a5-bd30-e9a36c2dae40.jpg?v=1768276515","url":"https:\/\/rndmate.com\/products\/nsj-v5664-20ug","provider":"알앤디메이트","version":"1.0","type":"link"}