{"product_id":"nsj-v7769saf-100ug","title":"CD32 Antibody, 100 ug","description":"\u003cp\u003e\u003cstrong\u003eThis CD32 antibody binds most strongly to the IIa isoforms of CD32 (FcRII)\u003c\/strong\u003e, a type 1 transmembrane glycoprotein that mediates several functions including phagocytosis, cytotoxicity, and immunomodulation as well as platelet aggregation. Three genes (A, B, and C) encode CD32 and at least 6 isoforms are generated via alternative mRNA splicing, i.e., IIa1, IIa2, IIb1, IIb2, IIb3 and IIc. Monocytes\/macrophages, placental trophoblasts and endothelial cells express all isoforms. In addition, the IIb isoform is expressed by B cells, and the IIa isoform by platelets, granulocytes and, weakly, by B cells. NK cells and neutrophils express Isoform IIc. CD32 binds weakly to the Fc region of monomeric IgG but more strongly to IgG aggregates and immune complexes.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":48534302851296,"sku":"V7769SAF-100UG","price":559.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/files\/get_image_3f12be2b-e6e1-46b6-a97b-235c89f879ce.jpg?v=1768272780","url":"https:\/\/rndmate.com\/products\/nsj-v7769saf-100ug","provider":"알앤디메이트","version":"1.0","type":"link"}