{"product_id":"nsj-v7966saf-100ug","title":"MTF1 Antibody \/ Metal regulatory transcription factor 1, 100 ug","description":"\u003cp\u003eThe metal-responsive element (MRE)-binding transcription factor (MTF-1) stimulates the expression of metallothioneins in response to the exposure of cells to heavy metals. MTF-1 contains six zinc fingers in the DNA binding domain. The phosphorylation of MTF-1 in response to metal exposure appears to play a significant role in the ability of MTF-1 to activate metallothionein transcription. In addition to its role in metallothionein activation, MTF-1 is involved in a post-transcription regulatory complex for ribosomal protein S25. MTF-1, La and p53 inhibit the nuclear export of S25 mRNA in response to nutrient depravation. Furthermore, MTF-1 acts as a chromatin insulator on integrated transgenes in cultured cells to insulate active loci against chromatin silencing.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":48534282993888,"sku":"V7966SAF-100UG","price":559.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/files\/get_image_4619b84b-81f5-473f-bca3-227095b0e1f0.jpg?v=1768272168","url":"https:\/\/rndmate.com\/products\/nsj-v7966saf-100ug","provider":"알앤디메이트","version":"1.0","type":"link"}