{"product_id":"nsj-v8291saf-100ug","title":"Cig2 Antibody, 100 ug","description":"\u003cp\u003eCig2 is a cyclin that functions as the catalytic subunit of cyclin-dependent kinases (Cdks) in the fission yeast Schizosaccharomyces pombe. It is a B-type, S phase cyclin that is required for both the G1\/S and G2\/M cell cycle transitions and is expressed in a sharp spike that peaks during the G1\/S period. Cig2 binds to Cdc2 (Cdk), and the resulting Cdc2\/Cig2 complex controls the G1\/S transition of the cell cycle. Disruption of Cig2 delays the onset of mitosis. The expression of the Cig2 gene is dependent on Mlu1-binding factor (MBF), and the protein is destroyed during anaphase by the APC\/cyclosome (APC\/C) and Skp1\/Cullin-1\/F-box (SCF), thereby ensuring the spike expression pattern of Cig2. SCF regulates Cig2 levels in a dual manner, transcriptionally and post-translationally, while APC\/C only destroys the protein.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":48534228467936,"sku":"V8291SAF-100UG","price":559.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/files\/get_image_bbfdf5e8-8b0f-48ec-8cdf-9bc336c78a71.jpg?v=1768271084","url":"https:\/\/rndmate.com\/products\/nsj-v8291saf-100ug","provider":"알앤디메이트","version":"1.0","type":"link"}