{"product_id":"pertussis-toxin-bordetella-pertussis","title":"Pertussis toxin (Bordetella pertussis)","description":"\u003cdiv class=\"fb_smallest fb_8-12_smallest margin-bottom-normal\"\u003e\n\u003cdiv class=\"margin-bottom-normal\"\u003e\n\u003cdiv class=\"c-GenericProductOverview__LabelText\"\u003e\n\u003cdiv\u003eReplaces Prod. #:\u003cspan\u003e \u003c\/span\u003e\u003cb\u003eALX-630-003\u003c\/b\u003e\n\u003c\/div\u003e\n\u003cbr\u003e\n\u003cdiv class=\"productfeatures\"\u003e\n\u003cul\u003e\n\u003cli\u003eHigher specificity and sensitivity\u003c\/li\u003e\n\u003cli\u003eMinimal lot-to-lot variation\u003c\/li\u003e\n\u003cli\u003eReproducible scale-up for bulk quantities\u003c\/li\u003e\n\u003cli\u003eLyophilized format for extended shelf-life\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ca name=\"Specifications\"\u003e\u003c\/a\u003e\u003cspan\u003e\u003c\/span\u003e\n\u003ch3 class=\"singleh3\"\u003eProduct Details\u003c\/h3\u003e\n\u003ctable class=\"productspecification\" border=\"0\" cellspacing=\"0\" cellpadding=\"0\"\u003e\n\u003ccolgroup\u003e\n\u003ccol width=\"214\"\u003e\n\u003ccol width=\"448\"\u003e\n\u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd valign=\"top\"\u003e\u003cb\u003eAlternative Name:\u003c\/b\u003e\u003c\/td\u003e\n\u003ctd valign=\"top\"\u003eIslet-activating protein, PTX, Holotoxin\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"subitemruler\" colspan=\"2\"\u003e \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"top\"\u003e\u003cb\u003eSource:\u003c\/b\u003e\u003c\/td\u003e\n\u003ctd valign=\"top\"\u003eFrom\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eBordetella pertussis,\u003cspan\u003e \u003c\/span\u003e\u003c\/em\u003estrain 165.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"subitemruler\" colspan=\"2\"\u003e \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"top\"\u003e\u003cb\u003eCAS:\u003c\/b\u003e\u003c\/td\u003e\n\u003ctd valign=\"top\"\u003e70323-44-3\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"subitemruler\" colspan=\"2\"\u003e \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"top\"\u003e\u003cb\u003eFormulation:\u003c\/b\u003e\u003c\/td\u003e\n\u003ctd valign=\"top\"\u003eLyophilized. Containing sodium phosphate and sodium chloride.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"subitemruler\" colspan=\"2\"\u003e \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"top\"\u003e\u003cb\u003ePurity:\u003c\/b\u003e\u003c\/td\u003e\n\u003ctd valign=\"top\"\u003e≥95%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"subitemruler\" colspan=\"2\"\u003e \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"top\"\u003e\u003cb\u003ePurity Detail:\u003c\/b\u003e\u003c\/td\u003e\n\u003ctd valign=\"top\"\u003ePurified by SDS-PAGE.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"subitemruler\" colspan=\"2\"\u003e \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"top\"\u003e\u003cb\u003eShipping:\u003c\/b\u003e\u003c\/td\u003e\n\u003ctd valign=\"top\"\u003eAmbient Temperature\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"subitemruler\" colspan=\"2\"\u003e \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"top\"\u003e\u003cb\u003eLong Term Storage:\u003c\/b\u003e\u003c\/td\u003e\n\u003ctd valign=\"top\"\u003e+4°C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"subitemruler\" colspan=\"2\"\u003e \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"top\"\u003e\u003cb\u003eUse\/Stability:\u003c\/b\u003e\u003c\/td\u003e\n\u003ctd valign=\"top\"\u003eThis preparation is lyophilized, aseptically packaged and sealed under vacuum. Do not vortex. Store at 4°C prior to and following reconstitution. Do not freeze. This toxin is considered to be biologically active. The lyophilized preparation will remain active for at least one year. After reconstitution with sterile water this product should remain active for at least six months if stored at 4°C. Each vial when reconstituted to 500 μl with sterile distilled water, contains 50.0 μg of pertussis toxin in 10 mM sodium phosphate buffer with 50 mM sodium chloride at pH 7.0. The toxin is not completely soluble and the resulting suspension should be made uniform by gentle mixing, not vortexing, prior to withdrawing aliquots. Do not sterile filter. For use with purified G proteins, the toxin must be structurally converted to artificially create a form of the toxin that interacts directly with G proteins. See Kaslow et al. (1987)\u003cbr\u003e\u003cbr\u003eThis product should be used only by technically qualified personnel. Good laboratory technique should be employed: Avoid mouth pipetting; wear gloves and other protective clothing; avoid inhalation; avoid contact with skin or open wounds; thoroughly wash any area of the body that comes in contact with the toxin with soap and water; wash eyes with water for fifteen minutes; exercise care when handling in hypodermic needles to avoid inadvertent intravenous or subcutaneous injection.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"subitemruler\" colspan=\"2\"\u003e \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"top\"\u003e\u003cb\u003eHandling:\u003c\/b\u003e\u003c\/td\u003e\n\u003ctd valign=\"top\"\u003eAseptically packed, sealed under vacuum. Do not vortex. Do not freeze.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"subitemruler\" colspan=\"2\"\u003e \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"top\"\u003e\u003cb\u003eScientific Background:\u003c\/b\u003e\u003c\/td\u003e\n\u003ctd valign=\"top\"\u003ePertussis toxin consists of an enzymatically active A protomer subunit (S-1) which possesses both NAD\u003csup\u003e+\u003c\/sup\u003e\u003cspan\u003e \u003c\/span\u003eglycohydrolase and ADP-ribosyltransferase activities and a B oligomer subunit (S-2, S-3, S-4, and S-5) which is responsible for attachment of the native toxin to eukaryotic cell surfaces. Pertussis toxin uncouples G proteins from receptors by ADP ribosylating a cysteine near the carboxy-terminus of the A subunit.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"subitemruler\" colspan=\"2\"\u003e \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"top\"\u003e\u003cb\u003eRegulatory Status:\u003c\/b\u003e\u003c\/td\u003e\n\u003ctd valign=\"top\"\u003eRUO - Research Use Only\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Enzo Life Science","offers":[{"title":"Default Title","offer_id":44918828728544,"sku":"BML-G100-0050","price":0.0,"currency_code":"KRW","in_stock":true}],"url":"https:\/\/rndmate.com\/products\/pertussis-toxin-bordetella-pertussis","provider":"알앤디메이트","version":"1.0","type":"link"}