{"product_id":"rq4883","title":"tPA Antibody \/ Tissue Plasminogen Activator","description":"\u003cp\u003ePLAT is also known as tPA. This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug \/ Rabbit","offer_id":46767235432672,"sku":"RQ4883","price":439.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/files\/get_image_fd7b5c41-0f5c-4e35-a502-5947b2cce49d.jpg?v=1734466584","url":"https:\/\/rndmate.com\/products\/rq4883","provider":"알앤디메이트","version":"1.0","type":"link"}