{"product_id":"rq6027","title":"Mitofusin 1 Antibody \/ MFN1","description":"\u003cp\u003eMitofusin-1 is a protein that in humans is encoded by the MFN1 gene. It is an 80-90 kDa mitochondrial member of the dynamin family of molecules. It is ubiquitously expressed, and found in the outer mitochondrial membrane. The protein encoded by this gene is a mediator of mitochondrial fusion, and thereby contribute to the dynamic balance between fusion and fission that determines mitochondria morphology. MFN1 is known to form oligomers, either with itself or MFNï¿½2, and to undergo ubiquitination by MARCH5. MFNï¿½1 has two key domains. One is a coiledï¿½coil region that mediates MFNï¿½1: MFNï¿½1\/2 binding, and a second is a GTPase domain whose cleavage of GTP is necessary for membrane fusion. Overexpression of MFN1 caused perinuclear mitochondrial clustering.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug \/ Mouse","offer_id":46766784381152,"sku":"RQ6027","price":439.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/files\/get_image_7de7134d-5641-43c7-a017-3a7bd3b15e66.jpg?v=1734463119","url":"https:\/\/rndmate.com\/products\/rq6027","provider":"알앤디메이트","version":"1.0","type":"link"}