{"product_id":"upa-polyclonal-antibody-bt-lab","title":"uPA Polyclonal Antibody","description":"\u003cp\u003ePLAU (plasminogen activator, urokinase) encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in PLAU may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":42358305718496,"sku":"BT-AP09424","price":275.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/products\/BT_Lab_ab9d9d6f-6d96-4944-aebb-646a39d84f73.png?v=1644573628","url":"https:\/\/rndmate.com\/products\/upa-polyclonal-antibody-bt-lab","provider":"알앤디메이트","version":"1.0","type":"link"}