{"product_id":"v-atpase-c2-polyclonal-antibody-bt-lab","title":"V-ATPase C2 Polyclonal Antibody","description":"\u003cp\u003eATP6V1C2 encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A,three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. ATP6V1C2 encodes alternate transcriptional splice variants, encoding different V1 domain C subunit isoforms.\u003c\/p\u003e\n\u003cp\u003eThe V-ATPase C2 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of V-ATPase C2 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human V-ATPase C2 protein. The antibody has been purified using protein A affinity chromatography and is supplied as a liquid in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative.\u003cbr\u003e\u003cbr\u003eThe V-ATPase C2 Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been shown to specifically recognize V-ATPase C2 protein in human, mouse, and rat tissues and cell lines. The antibody has a high affinity for its target protein, with a reported dilution range of 1:1000 to 1:5000 for Western blotting and 1:100 to 1:500 for immunohistochemistry and immunofluorescence.\u003cbr\u003e\u003cbr\u003eThis antibody is an essential tool for researchers studying the function and regulation of V-ATPase C2 protein in various biological processes, including lysosomal acidification, bone resorption, and tumor metastasis. Its high specificity and sensitivity make it an ideal choice for detecting low levels of V-ATPase C2 protein in complex biological samples. The V-ATPase C2 Polyclonal Antibody is available in various sizes to meet the needs of different research applications.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":42358308798688,"sku":"BT-AP09481","price":275.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/products\/BT_Lab_69c3120f-6869-4642-aa92-9acada029a20.png?v=1644580047","url":"https:\/\/rndmate.com\/products\/v-atpase-c2-polyclonal-antibody-bt-lab","provider":"알앤디메이트","version":"1.0","type":"link"}