{"product_id":"v2592-100ug","title":"HLA-DRB1 Antibody Cocktail (MHC II)","description":"\u003cp\u003eThis mAb reacts with the beta-chain of HLA-DRB1 antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes\/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3\/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense cytoplasmic staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts. Loss of HLA-DR expression is related to tumor microenvironment and predicts adverse outcome in diffuse large B-cell lymphoma.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug \/ Mouse","offer_id":46765395443936,"sku":"V2592-100UG","price":539.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/files\/get_image_d238c641-7b6e-4add-9eb3-7736c70f467e.jpg?v=1734441311","url":"https:\/\/rndmate.com\/products\/v2592-100ug","provider":"알앤디메이트","version":"1.0","type":"link"}