{"product_id":"v4252-20ug","title":"SHP-1 Antibody \/ PTPN6","description":"\u003cp\u003ePTPN6, which is also designated as SHP-1 and PTP1C, is expressed primarily in hematopoietic cells and characterized by the presence of two SH2 domains N-terminal to the PTP domain. It maps to 12p13, a region commonly involved in leukemia-associated chromosomal abnormalities. SHP-1 plays a role in modulating intracellular signaling for various molecules. In T-cell lymphomas and other malignancies, SHP-1 phosphatase expression is lost, by a thus far undetermined mechanism. Preliminary studies suggest that it may be helpful in differentiating mantle\/marginal zone lymphomas (SHP-1+) from follicular lymphomas (SHP-1 negative).\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"20 ug \/ Mouse","offer_id":46764716032224,"sku":"V4252-20UG","price":249.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/files\/get_image_ac2439fd-5cd3-4a86-b8ec-4644b33a9154.jpg?v=1734425213","url":"https:\/\/rndmate.com\/products\/v4252-20ug","provider":"알앤디메이트","version":"1.0","type":"link"}