{"product_id":"v9710-100ug","title":"BCL11A Antibody \/ B-cell lymphoma\/leukemia 11A","description":"\u003cp\u003eBcl-11a (CtIP-1, EVI9, B cell chronic lymphocytic leukemia (CLL)\/lymphoma 11A) and Bcl-11b (CtIP-2, RIT1, B cell CLL\/lymphoma 11B) genes play crucial roles in lymphopoiesis and influence the progression of hematopoietic malignancies. Disruption of the Bcl-11b locus is linked to T cell acute lymphoblastic leukemia, and the loss of heterozygosity in mice results in T cell lymphoma. Bcl-11 proteins are related C2H2 zinc-finger transcription factors that act as transcriptional repressors. Bcl-11b can interact with the metastasis-associated proteins MTA1 and MTA2 through the amino-terminal region. Bcl-11a is essential for postnatal development and normal lymphopoiesis. The Bcl-11a mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with Bcl-6.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug \/ Mouse","offer_id":46702580039904,"sku":"V9710-100UG","price":539.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/files\/get_image_4ca7e598-6933-402e-9260-7c8db2a7d4a4.jpg?v=1733300559","url":"https:\/\/rndmate.com\/products\/v9710-100ug","provider":"알앤디메이트","version":"1.0","type":"link"}