{"product_id":"xpln-polyclonal-antibody-bt-lab","title":"XPLN Polyclonal Antibody","description":"\u003cp\u003eRho-like GTPases are involved in a variety of cellular processes, and they are activated by binding GTP and inactivated by conversion of GTP to GDP by their intrinsic GTPase activity. Guanine nucleotide exchange factors (GEFs) accelerate the GTPase activity of Rho GTPases by catalyzing their release of bound GDP. ARHGEF3 encodes a guanine nucleotide exchange factor, which specifically activates two members of the Rho GTPase family: rHOA and RHOB, both of which have a role in bone cell biology. It has been identified that genetic variation in this gene plays a role in the determination of bone mineral density (BMD), indicating the implication of this gene in postmenopausal osteoporosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\u003cp\u003eThe XPLN Polyclonal Antibody is a highly specific and sensitive antibody designed for use in various research applications. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a unique sequence of the XPLN protein. The resulting polyclonal antibody exhibits high affinity and specificity towards the XPLN protein, making it an ideal tool for detecting and quantifying XPLN expression levels in various biological samples.\u003cbr\u003e\u003cbr\u003eThe XPLN Polyclonal Antibody has been extensively validated for use in Western blotting, immunohistochemistry, and immunofluorescence assays. It has been shown to detect endogenous XPLN protein expression in a variety of tissues and cell lines, and can be used to study the role of XPLN in various physiological and pathological processes.\u003cbr\u003e\u003cbr\u003eThis antibody is supplied as a purified IgG fraction, and has been tested for its ability to recognize the XPLN protein in a variety of species, including human, mouse, and rat. It is recommended for use at a dilution of 1:1000 for Western blotting, and 1:200 for immunohistochemistry and immunofluorescence assays.\u003cbr\u003e\u003cbr\u003eOverall, the XPLN Polyclonal Antibody is a reliable and versatile tool for studying the expression and function of the XPLN protein in various research applications. Its high specificity and sensitivity make it an ideal choice for researchers looking to investigate the role of XPLN in various biological processes.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":42358315647200,"sku":"BT-AP09619","price":275.0,"currency_code":"KRW","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/9330\/8896\/products\/BT_Lab_07159bf3-5d36-4db9-a26c-7adce363ece4.png?v=1644572864","url":"https:\/\/rndmate.com\/products\/xpln-polyclonal-antibody-bt-lab","provider":"알앤디메이트","version":"1.0","type":"link"}