Autophagy

Autophagy is a highly conserved process in eukaryotes, involving the degradation of proteins and organelles. During autophagy, damaged proteins or organelles are enclosed by double-membrane

autophagosomes and then transported to lysosomes for degradation. The amino acids and other small molecules produced by this process can be reused by the cell, also providing energy.

Autophagy is the fundamental mechanism for the degradation and recycling of cellular components.It allows cells to break down damaged, aged, or nonfunctional organelles, rapidly supplying energy and raw materials to maintain normal cellular function. Autophagy is mainly divided into four stages: induction of autophagy, assembly and formation of autophagosomes, fusion of autophagosomes with lysosomes, and the final degradation process. This precisely regulated mechanism is crucial for cellular health and the overall function of the organism.


Related Antibodies

Target

Cat.#

Product Name

Reactivity

Application

ATG12

AMRe01661

ATG12 Rabbit Monoclonal Antibody

Human,Mouse

WB

ATG3

AMRe01690

ATG3 Rabbit Monoclonal Antibody

Human,Mouse,Rat

WB,IHC,ICC/IF

ATG7

AMRe01663

ATG7 Rabbit Monoclonal Antibody

Human,Mouse,Rat

WB

APRab03731

ATG7 Rabbit Polyclonal Antibody

Human,Mouse,Rat

WB

Bcl2

AMRe03755

Bcl2 Rabbit Monoclonal Antibody

Human,Mouse

WB,IHC

APRab03730

Bcl2 Rabbit Polyclonal Antibody

Human,Mouse

WB,IHC,ICC/IF

Beclin 1

AMRe04047

Beclin 1 Rabbit Monoclonal Antibody

Human,Mouse,Rat

WB

LAMP1

AMRe02205

LAMP1 Rabbit Monoclonal Antibody

Human

WB,IHC

LAMP2

AMRe01588

LAMP2 Rabbit Monoclonal Antibody

Human

WB,IHC

LC3

APRab03870

LC3A/B Rabbit Polyclonal Antibody

Human,Mouse,Rat

WB

AMRe02228

LC3A Rabbit Monoclonal Antibody

Human,Mouse,Rat

WB,IHC

mTOR

APRab03727

Phospho-mTOR (Ser2448) Rabbit Polyclonal Antibody

Human,Mouse,Pig

WB,IHC

RAB7

AMRe02508

Rab7 Rabbit Monoclonal Antibody

Human,Mouse

WB,IHC

AMRe02507

Rab7 Rabbit Monoclonal Antibody

Human,Mouse,Rat

WB,IHC,ICC/IF

SQSTM1/p62

APRab03719

SQSTM1/p62 Rabbit Polyclonal Antibody

Human,Mouse,Rat

WB,ICC/IF

블로그로 돌아가기