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siRNA(Oligo Drugs) Study: Role of GalNAc-siRNA ...

siRNA(Oligo Drugs) Study: Role of GalNAc-siRNA Conjugates in Lysosomal Stability and siRNA Delivery for Overcoming siRNA Escape Keywords: GalNAc-siRNA, siRNA Delivery, siRNA Escape, Liver Lysosomes, Hepatocyte Lysosomes, Tritosome, Lysosome Catabolism,...

ADC Linker Performance: Payload Release, Liver ...

ADC Linker Performance: Payload Release, Liver Lysosome Catabolism, and Lysosomal Stability Mediated by Cathepsin B in DS8201a and GGFG-DxD Systems Keywords: ADC linker, Payload release, liver lysosome, lysosomal stability, lysosome...

N-Nitrosamines: An Enhanced Ames Test with Hams...

N-Nitrosamines: An Enhanced Ames Test with Hamster liver S9 Keywords: N-Nitrosamines, NDSRIs, OECD 471, Enhanced Ames test, Hamster liver S9, Cytochrome P450 enzymes, Mutation Test IPHASE Products Product Name  Specification...

[KO Validated] CDKN1A/p21 Rabbit mAb

The p53-p21-RB axis regulates the transcription of numerous genes critical for cell cycle control. p53 activation induces p21/CDKN1A, which inhibits cyclin-CDK complexes, leading to RB hypophosphorylation and repression of E2F-dependent...

2025 CUSABIO Monthly Citation Review

2025 CUSABIO Monthly Citation Review Top 1 Article Title: Neurotensin-neurotensin receptor 2 signaling in adipocytes suppresses food intake through regulating ceramide metabolism Journal Name: Cell Research Impact Factor: 28.4 CUSABIO Citation Product: Mouse...

Engineered Patelets as Targeted Protein Degrade...

Engineered Patelets as Targeted Protein Degraders and Application to Breast Cancer Models   ●Publication Date: 03 December 2024 ●Journal: Nature Biotechnology ●Impact Factor: 33.1 ●DOI: 10.1038/s41587-024-02494-8 Keywords Engineered platelets Heat shock protein 90 (HSP90) Breast...