Ferroptosis is a recently discovered form of regulated cell death that depends on ferrous iron ions and involves the high expression of unsaturated fatty acids on the cell membrane, leading to lipid
peroxidation and membrane damage. Morphologically, the characteristics of ferroptosis include mitochondrial shrinkage and increased membrane thickness. In terms of cellular components, it is characterized by lipid peroxidation and elevated levels of reactive oxygen species (ROS), which can be induced by multiple signaling pathways. Research indicates that the key regulatory mechanisms of ferroptosis involve the homeostasis of redox and iron metabolism.
Related Antibodies
Target |
Cat.# |
Product Name |
Reactivity |
Application |
ACSL4 |
AMRe03771 |
FACL4 Rabbit Monoclonal Antibody |
Human,Mouse,Rat |
WB,IHC |
Ferritin |
AMRe01562 |
Ferritin Heavy Chain Rabbit Monoclonal Antibody |
Human,Mouse,Rat,Hamster |
WB,ICC/IF |
FSP1 |
APRab03391 |
AIFM2/FSP1 Rabbit Polyclonal Antibody |
Human,Mouse,Monkey |
WB,ELISA |
GPX4 |
AMRe02041 |
Glutathione Peroxidase 4 Rabbit Monoclonal Antibody |
Human,Rat,Mouse |
WB |
HO-1 |
AMRe03776 |
Heme Oxygenase 1 Rabbit Monoclonal Antibody |
Human,Mouse,Rat |
WB,IHC |
HSP27 |
AMRe02122 |
Hsp27 Rabbit Monoclonal Antibody |
Human,Mouse |
WB,IHC |
NRF2 |
AMRe03900 |
Phospho-Nrf2 (Ser40) Rabbit Monoclonal Antibody |
Human |
WB |
ρ53 |
AMRe02387 |
p53 Rabbit Monoclonal Antibody |
Human |
WB,ICC/IF |
APRab03397 |
p53 Rabbit Polyclonal Antibody |
Human,Mouse,Rat,Monkey |
WB,ELISA |
|
APRab00821 |
Phospho-p53 (Ser15) Rabbit Polyclonal Antibody |
Human,Rat |
WB,IHC,IHC,ICC/IF,ELISA |
|
SLC7A11 |
AMRe03803 |
xCT Rabbit Monoclonal Antibody |
Human,Mouse |
WB |
Transferrin Receptor/CD71 |
AMRe02710 |
Transferrin Receptor 1 Rabbit Monoclonal Antibody |
Human |
WB,ICC/IF |
VDAC |
AMRe02754 |
VDAC1 Rabbit Monoclonal Antibody |
Human,Mouse,Rat |
WB,IHC |