From Isolation to Innovation: Revolutionize Your EV Research

Need a gentle, rapid, and efficient method to isolate EVs?

Then here is your solution!

Tangential flow filtration is gaining increasing recognition from the EV research community.

TFF delivers it all: rapid sample processing, high yields, and easy scale up for mass production. Plus, pair it with size exclusion chromatography for further purification making your EV samples ready for downstream applications.

At HansaBioMed Life Sciences, we offer three TFF options, mainly distinguished by the pore size of the filter:

TFF MVs

200nm pores can be used to separate large EVs from small EVs

TFF EVs

50nm pores separate EVs from non-EV sources based on their size

TFF Easy

With 5nm pores, you can concentrate your sample from 1 liter down to <10ml

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These filters, can also be combined for in series use, they are sterile and reusable. This makes them an ideal to isolate EVs from biofluids, cell culture media, or plant extracts.

FURTHER INFORMATION

How about some additional support from an orthogonal method to the size-based approach of TFF?

ExoTFF is the solution for you combining size- based separation with charge-based filtration is perfect for you.

This product is a combination of TFF-EVs with ExoFilter from our

partner Microgentas. It combines charge-based filtration with the size-based approach of TFF, resulting in a much higher purity of EVs.

Thanks to its simplified design, ExoTFF ensures rapid separation of EVs from the fluid matrix while retaining particle morphology and integrity. Its efficiency makes it ideal to work with harsh matrices including plasma and serum.

Curious about the cutting-edge potential of plant-derived EVs being used in cosmetics, food science, and beyond?

HansaBioMed Life Sciences offers EV-like nanoparticles from five different sources: seaberry, ginger, garlic, onion, and potato!

Plant-derived EVs offer compelling advantages over animal sources: abundant availability, simplified access, cost-effectiveness, and minimal ethical considerations. These features make them attractive for novel applications not only in clinical settings, but also in food, cosmetics, and agriculture industries.

With this in mind, we offer purified EVs from different plant sources for research use. These EVs are purified by TFF and well-characterized in terms of size, concentration, and marker expression. Thanks to lyophilization, they can be shipped at 4°C and be stored for up to 3 years.

Upon request, custom made EVs from additional plant sources can also be produced.