anti- CACNA1B antibody

Unlock the mysteries of CACNA1B with our Anti-CACNA1B Antibody, now available in a 100µg vial. CACNA1B, a subunit of voltage-gated calcium channels, is essential for regulating calcium ion influx and is involved in various physiological processes, including neurotransmission and synaptic plasticity.

Our meticulously developed and rigorously tested Anti-CACNA1B Antibody empowers you to explore the functions and roles of CACNA1B with precision and accuracy. Whether you're investigating its roles in neuronal excitability, channelopathies, or its implications in neurological disorders, this antibody provides the specificity and sensitivity necessary for reliable results.

This versatile antibody is optimized for various applications, including immunohistochemistry, Western blotting, and immunoprecipitation. With its robust performance, you can confidently investigate CACNA1B in diverse experimental setups.

Each 100µg vial of this antibody offers value and flexibility, allowing you to advance scientific knowledge and contribute to our understanding of CACNA1B in both normal neuronal function and pathological conditions with confidence.

Product Name

CACNA1B antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Voltage-sensitive calcium channels(VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-voltage activated'(HVA) group and are blocked by omega-conotoxin-GVIA(omega-CTx-GVIA) and by omega-agatoxin-IIIA(omega-Aga-IIIA). They are however insensitive to dihydropyridines(DHP), and omega-agatoxin-IVA(omega-Aga-IVA). Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons.

IMMUNOGEN INFORMATION

Immunogen

calcium channel, voltage-dependent, N type, alpha 1B subunit

Synonyms

BIII, Brain calcium channel III, CACH5, CACNA1B, CACNL1A5, CACNN, Cav2.2

Observed MW

262 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:200-1:1000; IHC: 1:50-1:500

UNIPROT INFORMATION

UniProt ID

Q00975

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