anti- MYCN antibody

anti- MYCN antibody

Product Name

MYCN antibody

Catalogue No.

FNab05460

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

IMMUNOGEN INFORMATION

Immunogen

v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)

Synonyms

BHLHE37, NMYC

Observed MW

45 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P04198

IMAGES

Immunohistochemistry of paraffin-embedded mouse brain using FNab05460(MYCN antibody) at dilution of 1:100

mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab05460(MYCN Antibody) at dilution of 1:1000