anti- SHMT2 antibody

anti- SHMT2 antibody

Product Name

SHMT2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5, 10-methylene tetrahydrofolate. The encoded product is primarily responsible for glycine synthesis. The activity of the encoded protein has been suggested to be the primary source of intracellular glycine. The gene which encodes the cytosolic form of this enzyme is located on chromosome 17. Alternative splicing results in multiple transcript variants.

IMMUNOGEN INFORMATION

Immunogen

serine hydroxymethyltransferase 2 (mitochondrial)

Synonyms

GLYA, HEL-S-51e, SHMT

Observed MW

55 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P34897

IMAGES

Immunohistochemistry of paraffin-embedded rat kidney using FNab07851(SHMT2 antibody) at dilution of 1:100

HeLa cells were subjected to SDS PAGE followed by western blot with FNab07851(SHMT2 antibody) at dilution of 1:1000