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ELK Biotechnology

SKU(재고 관리 코드):ES5239

Fibrinogen β Rabbit Polyclonal Antibody

Fibrinogen β Rabbit Polyclonal Antibody

Size

Fibrinogen β Rabbit Polyclonal Antibody

Overview

Product name: Fibrinogen β rabbit pAb
Alternative Names: FGB; Fibrinogen beta chain
Applications: WB;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: Synthesized peptide derived from the Internal region of human Fibrinogen β.
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 55kD
GeneID(Human): 2244
Human Swiss-Prot No: P02675
Cellular localization: Secreted .
Background: The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014],
Species Reactivity: Human;Rat;Mouse;
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