This antibody reacts with a 180 kDa protein, known as Flt-1 or vascular endothelial growth factor receptor 1 (VEGFR1). Flt-1 is a cell membrane receptor kinase. Flk-1 has a high affinity receptor for vascular endothelial growth factor and is putatively involved in the growth of endothelial cells and angiogenesis.
