COL11A2 (P1232) polyclonal antibody

COL11A2 (collagen, type XI, alpha 2), also known as Collagen α2 Type XI, HKE5, PARP, STL3, DFNA13 or DFNB53, is a 1,736 amino acid secreted protein that contains one TSP N-terminal domain and is thought to play an essential role in fibrillogenesis, specifically by controlling the lateral growth of collagen fibrils. Defects in the gene encoding COL11A2 are the cause of Stickler syndrome type 3 (STL3), autosomal recessive otospondylomegaepiphyseal dysplasia (OSMED), Weissenbacher-Zweymueller syndrome (WZS) and non-syndromic sensorineural deafness autosomal dominant type 13 (DFNA13). Eight isoforms of COL11A2 exist due to alternative splicing events.