Bioworld
SKU(재고 관리 코드):MB66207
Thyroglobulin monoclonal antibody
Thyroglobulin monoclonal antibody
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Acts as a substrate for the production of iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3) (PubMed:32025030, PubMed:17532758).
The synthesis of T3 and T4 involves iodination of selected tyrosine residues of TG/thyroglobulin followed by their oxidative coupling in the thyroid follicle lumen (PubMed:32025030).
Following TG re-internalization and lysosomal-mediated proteolysis, T3 and T4 are released from the polypeptide backbone leading to their secretion into the bloodstream (PubMed:32025030).
One dimer produces 7 thyroid hormone molecules (PubMed:32025030).
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