MDH2 polyclonal antibody

MDH2 (malate dehydrogenase, NAD mitochondrial), also known as MDH, MOR1 or M-MDH, is a 338 amino acid that belongs to the LDH/MDH superfamily. MDH2 localizes to the mitochondria and may play a critical role in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. MDH2 utilizes the NAD/NADH cofactor system in the citric acid cycle to catalyze the reversible oxidation of malate to oxaloacetate. Oxaloacetate is involved in many important metabolic pathways including amino acid synthesis, gluconeogenesis and facilitation of the exchange of metabolites between cytoplasm and subcellular organelles.