MGAT1 polyclonal antibody

Monoacylglycerol O-acyltransferase (MGAT) catalyzes diacylglycerol (a precursor to triacylglycerol) synthesis. MGAT is important in intestinal absorption of dietary fat because resynthesis of triacylglycerol is needed for the assembly of the lipoproteins that transport absorbed fat to tissues. MGAT1 is expressed in stomach, kidney, liver and adipose tissue but is not found in the intestine. On the contrary, MGAT2 (monoacylglycerol O-acyltransferase 2) is highly expressed in the small intestine as well as in kidney, liver, colon, stomach and white adipose tissue. MGAT 3 (monoacylglycerol O-acyltransferase 3) is highly homologous to MGAT1 and MGAT2. The expression of MGAT3 is restricted to the gastrointestinal tract, most concentrated in the ileum.