RPL14 polyclonal antibody

Ribosomes, the organelles that catalyze protein synthesis, are composed of a small subunit (40S) and a large subunit (60S) that consist of over 80 distinct ribosomal proteins. Mammalian ribosomal proteins are encoded by multigene families that contain processed pseudogenes and one functional intron-containing gene within their coding regions. Ribosomal Protein L14, also known as L14, RPL14, RL14, CTG-B33 or CAG-ISL-7, is a 213 amino acid protein that is a component of the 60S subunit. Localized to the cytoplasm, Ribosomal Protein L14 belongs to the L14e family of ribosomal proteins and functions in protein synthesis. Ribosomal Protein L14 contains a basic region-leucine zipper (bZIP)-like domain and a polymorphic polyalanine tract. The polyalanine tract is believed to participate in transcription regulation. Like most ribosomal proteins, Ribosomal Protein L14 exists as multiple processed pseudogenes that are scattered throughout the genome.