RPS14 polyclonal antibody

Ribosomes, the organelles that catalyze protein synthesis, are composed of a small subunit (40S) and a large subunit (60S) that consist of over 80 distinct ribosomal proteins. Mammalian ribosomal proteins are encoded by multigene families that contain processed pseudogenes and one functional intron-containing gene within their coding regions. Ribosomal Protein S14, also known as RPS14 or EMTB, is a 151 amino acid component of the small ribosomal 40S subunit. Localized to the cytoplasm, Ribosomal Protein S14 is a member of the S11P family of ribosomal proteins and is highly conserved among several species. Defects in the gene encoding Ribosomal Protein S14 may cause resistance to emetine, a protein synthesis inhibitor found in Chinese hamster ovary cells. Multiple isoforms of this protein exist due to alternative splicing events.