UQCRFS1 polyclonal antibody

Cytochrome c is a well characterized, mobile electron transport protein that is essential to energy conversion in all aerobic organisms. Cytochrome b associates with cytochrome c subunit 1 and the Rieske protein to form complex III (also designated cytochrome bc1 complex), which is involved in cellular respiration. Ubiquinol cytochrome c reductase (UQCRFS1), also referred to as Rieske iron-sulfur protein (Rieske FeS), represents an important subunit of complex III of the mitochondrial respiratory chain. This complex transfers electrons from ubiquinol to cytochrome c. The gene encoding for Rieske FeS may be involved in the development of a more aggressive phenotype of breast cancer.