제품 정보로 건너뛰기
1 1

Bioworld

SKU(재고 관리 코드):BS94067

Src (Phospho-Y419) polyclonal antibody

Src (Phospho-Y419) polyclonal antibody

Size
Host
Reactivity

The Src family of protein tyrosine kinases, which includes Src, Lyn, Fyn, Yes, Lck, Blk, and Hck, are important in the regulation of growth and differentiation of eukaryotic cells. Src activity is regulated by tyrosine phosphorylation at two sites, but with opposing effects. While phosphorylation at Tyr416 in the activation loop of the kinase domain upregulates enzyme activity, phosphorylation at Tyr527 in the carboxy-terminal tail by Csk renders the enzyme less active.

전체 세부 정보 보기