anti- SORBS2 antibody

anti- SORBS2 antibody

Product Name

SORBS2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 or with AKT1 and PAK1, thus mediating AKT1-mediated activation of PAK1. May play a role in the regulation of pancreatic cell adhesion, possibly by acting on WASF1 phosphorylation, enhancing phosphorylation by ABL1, as well as dephosphorylation by PTPN12(PubMed:18559503). Isoform 6 increases water and sodium absorption in the intestine and gall-bladder.

IMMUNOGEN INFORMATION

Immunogen

sorbin and SH3 domain containing 2

Synonyms

ARGBP2, KIAA0777

APPLICATION

Tested Application

ELISA, IP

Recommended Dilution

IP: 1:200-1:2000

UNIPROT INFORMATION

UniProt ID

O94875

IMAGES

IP Result of anti-SORBS2 (IP:FNab08112, 4ug; Detection:FNab08112 1:500) with mouse heart tissue lysate 4000ug.