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SKU(재고 관리 코드):PAA552Rb51

Polyclonal Antibody to Tissue Inhibitors Of Metalloproteinase 1 (TIMP1)

Polyclonal Antibody to Tissue Inhibitors Of Metalloproteinase 1 (TIMP1)

UOM
Concentration
Organism species

Western blotting: 0.2-2µg/mL;1:250-2500
Immunohistochemistry: 5-20µg/mL;1:25-100
Immunocytochemistry: 5-20µg/mL;1:25-100
Optimal working dilutions must be determined by end user.

Product No.

PAA552Rb51

Organism Species

Oryctolagus cuniculus (Rabbit).

Source

Polyclonal antibody preparation

Host

Guinea pig

Potency

n/a

Ig Type

IgG

Purification

Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Label

APC

Immunogen

n/a

Buffer Formulation

PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

Traits

Liquid

Concentration

500µg/mL

Organism Species More

n/a

Applications

WB; IHC; ICC; IP.

If the antibody is used in flow cytometry, please check FCM antibodies.

UOM

20µl 100µl 200µl 1ml 10ml

SPECIFITY

The antibody is a cavia polyclonal antibody raised against TIMP1. It has been selected for its ability to recognize TIMP1 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.2-2µg/mL;1:250-2500
Immunohistochemistry: 5-20µg/mL;1:25-100
Immunocytochemistry: 5-20µg/mL;1:25-100
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Magazine

Citations

Experimental & Translational Stroke Medicine

Early outcome and blood-brain barrier integrity after co-administered thrombolysis and hyperbaric oxygenation in experimental stroke PubMed: 21679435

PLoS ONE

A Combinatorial Relative Mass Value Evaluation of Endogenous Bioactive Proteins in Three-Dimensional Cultured Nucleus Pulposus Cells of Herniated Intervertebral Discs: Identification of Potential Target Proteins for Gene Therapeutic Approaches Plosone: Source

Polski Przeglad Chirurgiczny

Concentration of gelatinases and their tissue inhibitors in pancreatic inflammatory and neoplastic tumors and their influence on the early postoperative course Pubmed: 23585206

Thromb Haemost.

Analysis of the expression of nine secreted matrix metalloproteinases and their endogenous inhibitors in the brain of mice subjected to ischaemic stroke Pubmed:24671655

The Scientific World Journal

Pass-predicted hepatoprotective activity of Caesalpinia sappan in thioacetamide-induced liver fibrosis in rats Pubmed:24701154

PLOS ONE

The Complementary Effects of Atorvastatin and Exercise Treatment on the Composition and Stability of the Atherosclerotic Plaques in ApoE Knockout Mice Pubmed:25264981

Mediators of Inflammation

Metalloproteinases and Their Tissue Inhibitors in Comparison between Different Chronic Pneumopathies in the Horse Journals: Mi

PLOS

Adiponectin Attenuates Lung Fibroblasts Activation and Pulmonary Fibrosis Induced by Paraquat PubMed: 25945502

Canadian Journal of Physiology and Pharmacology

Modified Citrus Pectin stops progression of liver fibrosis by inhibiting galactin-3 and inducing apoptosis of stellate cells Doi: Abs

PLoS One

Silencing of Paternally Expressed Gene 10 Inhibits Trophoblast Proliferation and Invasion PubMed: 26680220

Kyselov

Влияние диуретиков с антиальдостероновым действием на состояние межклеточного матрикса и раннее постинфарктное ремоделирование левого … Article: View

Оригинальные исследования / Original researches

матриксу та ранн Article: Viewfile

Basic Research

CTGF upreCavia (Guinea pig )lation correlates with MMP-9 level in airway remodeling in a murine model of asthma Journal:27699

J Orthop Res.

Tetrandrine suppresses articular inflammatory response by inhibiting pro-inflammatory factors via NF-κB inactivation. Pubmed:26748661

Int Wound J.

From varices to venous ulceration: the story of chronic venous disease described by metalloproteinases. Pubmed:26991748

Am J Pathol. 

Serum Osteopontin as a Novel Biomarker for Muscle Regeneration in Duchenne Muscular Dystrophy. Pubmed:26963343

Journal of Orthopaedic Research

Tetrandrine suppresses articular inflammatory response by inhibiting pro‐inflammatory factors via NF‐κB inactivation pubmed:26748661

Canadian Journal of Veterinary Research

Evaluation of hyaluronic acid, procollagen type III N-terminal peptide, and tissue inhibitor of matrix metalloproteinase-1 as serum markers of canine hepatic fibrosis pubmed:27733785

BMC Veterinary Research

Metalloproteinases and their inhibitors are influenced by inhalative glucocorticoid therapy incombination with environmental dust reduction in equine recurrent airway obstruction. pubmed:27938355

Journal of Cellular Physiology

Increased Chondrogenic Potential of Mesenchymal Cells From Adipose Tissue Versus Bone Marrow‐Derived Cells in Osteoarthritic In Vitro Models pubmed:27739057

Toxicology and Applied Pharmacology

Sildenafil protects against bile duct ligation induced hepaticfibrosis in rats: Potential role for silent information regulator 1 (SIRT1) pubmed:28974454

Journal of Applied Animal Research

Hypoxia enhances secretion of matrix metalloproteinases in bovine dermal fibroblasts:an in vitro approach to bovine digital dermatitis 10.108:09712119.2017.1335208

Cellular Physiology and Biochemistry

The MiR-495/Annexin A3/P53 Axis Inhibits the Invasion and EMT of Colorectal Cancer Cells pubmed:29224019

International Wound Journal

From varices to venous ulceration: the story of chronic venous disease described by metalloproteinases pubmed:26991748

Archives of Medical Science

CTGF upregulation correlates with MMP-9 level in airway remodeling in a murine model of asthma. pubmed:28507585

APMIS

Hepatoprotectivity of Panduratin A against liver damage: demonstration with a rat model of cirrhosis induced by thioacetamide Pubmed:30058214

Journal of Applied Animal Research 

Hypoxia enhances secretion of matrix metalloproteinases in bovine dermal fibroblasts: an approach to bovine digital dermatitis 10.1080:09712119.2017.1335208


МАТРИКСНЫЕ МЕТАЛЛОПРОТЕИНАЗЫ: ЗНАЧЕНИЕ В РЕМОДЕЛИРОВАНИИ СЕРДЦА У ПАЦИЕНТОВ С ДИСПЛАЗИЕЙ СОЕДИНИТЕЛЬНОЙ ТКАНИ

Mediators of Inflammation

Metalloproteinases and their Inhibitors under the Course of Immunostimulation by CPG-ODN and Specific Antigen Inhalation in Equine Asthma

International Journal of Clinical and Experimental Medicine

Expression of MMP-9 and TIMP-1 in rat models of pressure ulcer and their significance

Oncology Research

MicroRNA-6884-5p regulates the proliferation, invasion and EMT of gastric cancer cells by directly targeting S100A16 Pubmed: 31796150

Open Medicine

Plasma matrix metalloproteinase-9 and tissue inhibitor of matrix metalloproteinase-1 as prognostic biomarkers in critically ill patients Pubmed: 32190734

Scientific Reports

Matrix metallopeptidase expression and modulation by transforming growth factor-β1 in equine endometrosis Pubmed: 31980722

JOURNAL OF THROMBOSIS AND THROMBOLYSIS

Extracellular matrix collagen biomarkers levels in patients with chronic thromboembolic pulmonary hypertension Pubmed: 33175289

Molecular Medicine Reports

MicroRNA-1 promotes cartilage matrix synthesis and regulates chondrocyte differentiation via post-transcriptional suppression of Ihh expression Pubmed: 32705199

International Journal of Environmental Research and Public Health

Biomarkers Facilitate the Assessment of Prognosis in Critically Ill Patients with Primary Brain Injury: A Cohort Study Pubmed: 32575870

.

Почечная дисфункция при преэклампсии: прогнозирование и дифференциальный диагноз. Часть 1

MEDIATORS OF INFLAMMATION

MMP-9 Concentration in Peritoneal Fluid Is a Valuable Biomarker Associated with Endotoxemia in Equine Colic 33488296

CLINICAL SCIENCE

Berberine accelerated wound healing by restoring TrxR1/JNK in diabetes 33491733

DOCSBAY

Intermittent Pacing Therapy Favorably Modulates Infarct Remodeling 28386775


EVALUATION OF DYNAMICS OF METALLOPROTEINASE ACTIVITY AND INDICATORS OF OXIDATIVE STRESS IN THE TREATMENT OF BURNS WITH A NEW DERIVATIVE OF N-ACETYL-6- AMINOHEXANOIC ACID

VETERINARY OPHTHALMOLOGY

Concentrations of tissue inhibitor of matrix metalloproteinase‐1 and hyaluronic acid in canine amniotic membranes cryopreserved for different time points and its … 34240563

Hum Brain Mapp

Deep transfer learning of structural magnetic resonance imaging fused with blood parameters improves brain age prediction 34913545


Catalog No.

Related products for research use of Oryctolagus cuniculus (Rabbit) Organism species

Applications (RESEARCH USE ONLY!)

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WB; IHC; ICC.

LAA552Rb81

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WB; IHC; ICC; IF.

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ELISA Kit for Tissue Inhibitors Of Metalloproteinase 1 (TIMP1)

Enzyme-linked immunosorbent assay for Antigen Detection.

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Magnetic Luminex Assay Kit for Tissue Inhibitors Of Metalloproteinase 1 (TIMP1) ,etc.

Magnetic Luminex Assay for Antigen Detection.

 

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