TAF II p100 Polyclonal Antibody

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. Transcription initiation factor TFIID subunit 5 that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. TAF5 encodes an integral subunit of TFIID associated with all transcriptionally competent forms of that complex. This subunit interacts strongly with two TFIID subunits that show similarity to histones H3 and H4, and it may participate in forming a nucleosome-like core in the TFIID complex. Alternative splicing results in multiple transcript variants.

The TAF II p100 Polyclonal Antibody is a highly reliable and efficient tool designed for the detection and analysis of TAF II p100 protein expression in various biological samples. This antibody is produced using advanced techniques, ensuring exceptional specificity and sensitivity.

With its superior performance, the TAF II p100 Polyclonal Antibody enables accurate identification and quantification of TAF II p100 protein levels, facilitating comprehensive research in the field of transcriptional regulation. It is particularly valuable for investigating the role of TAF II p100 in gene expression and its involvement in various cellular processes.

This antibody exhibits exceptional versatility, making it suitable for a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. Its robustness and consistency guarantee reliable and reproducible results, enabling researchers to obtain precise data for their experiments.

The TAF II p100 Polyclonal Antibody is meticulously validated to ensure its high quality and performance. It has been extensively tested on multiple cell lines and tissues, demonstrating its exceptional specificity and minimal cross-reactivity. This antibody exhibits minimal background noise, allowing for clear and accurate visualization of the target protein.

Furthermore, the TAF II p100 Polyclonal Antibody is manufactured in compliance with stringent quality control standards, ensuring batch-to-batch consistency and reliability. It is supplied in a convenient format, with various sizes available to meet the specific needs of different experiments.

In summary, the TAF II p100 Polyclonal Antibody is an indispensable tool for researchers studying TAF II p100 protein expression and its functional implications. Its exceptional specificity, sensitivity, and versatility make it an ideal choice for a wide range of applications, providing valuable insights into the intricate mechanisms of transcriptional regulation.