11 Beta-HSD1 Polyclonal Antibody

hydroxysteroid 11-beta dehydrogenase 1(HSD11B1) Homo sapiens The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.

The 11 Beta-HSD1 Polyclonal Antibody is a highly specific and sensitive antibody designed for use in various research applications. This antibody is produced using a polyclonal approach, which ensures a high degree of specificity and sensitivity. It is designed to target the 11 Beta-HSD1 protein, which is a key enzyme involved in the metabolism of cortisol and cortisone.

The antibody is suitable for use in a variety of applications, including Western blotting, immunohistochemistry, and ELISA. It has been extensively validated for use in research applications and is guaranteed to provide reliable and reproducible results. The 11 Beta-HSD1 Polyclonal Antibody is an essential tool for researchers studying the role of the 11 Beta-HSD1 protein in various physiological and pathological processes. It is available in various sizes and formats to suit different research needs. Order now and experience the high quality and reliability of this antibody for yourself.