11 Beta-HSD1 Polyclonal Antibody

Hydroxysteroid 11-beta dehydrogenase 1 encoded by HSD11B1 is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in HSD11B1 has been associated with obesity and insulin resistance in children. Mutations in HSD11B1 and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.

The 11 Beta-HSD1 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and quantification of 11 Beta-Hydroxysteroid Dehydrogenase 1 (11 Beta-HSD1) protein. This antibody has been meticulously developed and validated to ensure exceptional performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

With its polyclonal nature, this antibody exhibits a broad reactivity, enabling it to recognize and bind to multiple epitopes of the 11 Beta-HSD1 protein. This characteristic enhances the sensitivity and versatility of the antibody, making it an ideal choice for researchers and scientists working in diverse fields such as endocrinology, metabolism, and pharmacology.

The 11 Beta-HSD1 Polyclonal Antibody is produced using state-of-the-art techniques, ensuring high purity and batch-to-batch consistency. Rigorous quality control measures are implemented throughout the manufacturing process to guarantee optimal performance and reproducibility. Each lot of antibody is thoroughly tested to meet stringent criteria, ensuring reliable and accurate results.

This antibody demonstrates exceptional specificity, exhibiting minimal cross-reactivity with other related proteins. Its high affinity for the 11 Beta-HSD1 protein allows for precise and reliable detection, even in complex biological samples. The antibody's robust performance and low background noise contribute to the generation of clear and interpretable data.

The 11 Beta-HSD1 Polyclonal Antibody is supplied in a convenient and user-friendly format, allowing for easy handling and storage. It is provided as a liquid formulation, eliminating the need for time-consuming reconstitution steps. The antibody is stable under recommended storage conditions, ensuring long-term usability and reliability.

In summary, the 11 Beta-HSD1 Polyclonal Antibody is a superior tool for the detection and quantification of 11 Beta-HSD1 protein. Its exceptional specificity, sensitivity, and versatility make it an invaluable asset for researchers seeking to unravel the complexities of 11 Beta-HSD1 biology and its implications in various physiological and pathological processes.