5-LO Polyclonal Antibody

ALOX5 encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The arachidonate 5-lipoxygenasen, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Introducing the 5-LO Polyclonal Antibody, a highly specialized and meticulously developed product designed to cater to the needs of researchers and scientists in the field of immunology. This antibody, derived from a polyclonal source, exhibits exceptional specificity and sensitivity, making it an invaluable tool for various applications in the laboratory.

The 5-LO Polyclonal Antibody has been meticulously purified and validated to ensure optimal performance and reliability. With its ability to recognize and bind to the 5-lipoxygenase (5-LO) protein, this antibody enables precise detection and analysis of this crucial enzyme involved in the biosynthesis of leukotrienes.

Crafted with utmost precision, this antibody offers a wide range of applications, including immunohistochemistry, immunofluorescence, western blotting, and enzyme-linked immunosorbent assays (ELISA). Its versatility allows for comprehensive investigation of 5-LO expression and localization in various tissues and cell types, facilitating groundbreaking research in the field of inflammation, asthma, and other related disorders.

The 5-LO Polyclonal Antibody boasts exceptional performance characteristics, including high affinity, low background noise, and minimal cross-reactivity. Its superior sensitivity ensures accurate and reliable results, even in samples with low expression levels of 5-LO. Furthermore, this antibody exhibits excellent reproducibility, guaranteeing consistent outcomes across multiple experiments.

To ensure utmost quality, the 5-LO Polyclonal Antibody has undergone rigorous quality control measures, including validation in relevant experimental models and thorough testing for specificity and functionality. This stringent process ensures that researchers can confidently rely on this antibody for their scientific investigations.

In summary, the 5-LO Polyclonal Antibody stands as a pinnacle of excellence in the realm of immunological research. Its exceptional specificity, sensitivity, and versatility make it an indispensable tool for scientists and researchers seeking to unravel the intricate mechanisms underlying various inflammatory processes. With this antibody, groundbreaking discoveries and advancements in the field are within reach.