A Cyclase VIII Polyclonal Antibody

Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. The enzymatic activity is under the control of several hormones, and different polypeptides participate in the transduction of the signal from the receptor to the catalytic moiety. Stimulatory or inhibitory receptors (Rs and Ri) interact with G proteins (Gs and Gi) that exhibit GTPase activity and they modulate the activity of the catalytic subunit of the adenylyl cyclase.

Introducing the CYCLASE VIII Polyclonal Antibody, a highly specific and sensitive tool for the detection and quantification of CYCLASE VIII protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human CYCLASE VIII protein, followed by purification using protein A affinity chromatography.

The CYCLASE VIII Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It recognizes a single band of the expected size in Western blot analysis of human, mouse, and rat brain lysates, and shows minimal cross-reactivity with other CYCLASE isoforms.

This antibody is supplied as a liquid formulation in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative. It is recommended to store the antibody at -20°C or -80°C for long-term storage and to avoid repeated freeze-thaw cycles.

In summary, the CYCLASE VIII Polyclonal Antibody is a reliable and high-quality reagent for the detection and quantification of CYCLASE VIII protein in various biological samples. Its specificity and sensitivity make it an ideal tool for researchers studying the role of CYCLASE VIII in various physiological and pathological processes.