A2AP Polyclonal Antibody

This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin| which degrades fibrin and various other proteins. Consequently| the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency| which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene.