AACT Polyclonal Antibody

Alpha-1-antichymotrypsin encoded by SERPINA3 is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease

The AACT polyclonal antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of AACT protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human AACT protein. The resulting polyclonal antibody exhibits high affinity and specificity towards AACT protein, making it an ideal tool for various applications in research and diagnostics.

The AACT polyclonal antibody is purified using a combination of protein A and protein G chromatography, ensuring high purity and minimal cross-reactivity with other proteins. This antibody is suitable for use in various immunoassays, including Western blotting, ELISA, immunohistochemistry, and flow cytometry. It has been validated for use in human, mouse, and rat samples, making it a versatile tool for researchers working with different model organisms.

The AACT polyclonal antibody is supplied as a liquid formulation in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative. It is available in different sizes to meet the needs of different applications and budgets. This antibody is manufactured under strict quality control standards to ensure consistent performance and reproducibility.

In summary, the AACT polyclonal antibody is a reliable and high-quality reagent for the detection and quantification of AACT protein in various biological samples. Its high specificity, sensitivity, and versatility make it an essential tool for researchers and clinicians working in the fields of biochemistry, molecular biology, and clinical diagnostics.