Abi-1 Polyclonal Antibody

ABI1 encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein (abl interactor 1) plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t (10;11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14.

The Abi-1 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of Abelson interactor 1 (Abi-1) protein. This antibody is produced using advanced immunization techniques, ensuring high affinity and sensitivity for Abi-1 detection.

Abi-1 is a crucial component of various cellular processes, including actin cytoskeleton remodeling, cell migration, and cell adhesion. It plays a significant role in the regulation of cell morphology and motility, making it an essential protein for studying cellular dynamics and signaling pathways.

The Abi-1 Polyclonal Antibody exhibits exceptional performance in various applications, such as Western blotting, immunohistochemistry, and immunofluorescence. It recognizes endogenous levels of Abi-1 protein in a wide range of species, including human, mouse, and rat, making it suitable for diverse experimental settings.

With its high specificity and sensitivity, this antibody enables accurate and reliable detection of Abi-1 protein, facilitating comprehensive research in cellular biology, cancer biology, and developmental biology. Its robust performance and consistent results make it an indispensable tool for scientists and researchers in their pursuit of understanding the intricate mechanisms underlying cellular processes.

The Abi-1 Polyclonal Antibody is supplied in a convenient and ready-to-use format, ensuring ease of use and minimizing experimental variability. It is manufactured under stringent quality control measures to guarantee batch-to-batch consistency and reproducibility.

In summary, the Abi-1 Polyclonal Antibody is a superior research tool that offers exceptional performance, reliability, and versatility. Its high specificity and sensitivity make it an invaluable asset for scientists and researchers aiming to unravel the complexities of Abi-1 protein function and its involvement in various cellular processes.