Abl1/2 Polyclonal Antibody

ABL1 is a protooncogene that encodes a protein tyrosine kinase (ABL proto-oncogene 1, non-receptor tyrosine kinase) involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA-binding activity that is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function. ABL1 has been found fused to a variety of translocation partner genes in various leukemias, most notably the t (9;22) translocation that results in a fusion with the 5' end of the breakpoint cluster region gene (BCR; MIM:151410). Alternative splicing of this gene results in two transcript variants, which contain alternative first exons that are spliced to the remaining common exons.

Introducing the ABL1/2 Polyclonal Antibody, a highly specialized and meticulously developed product designed to cater to the needs of scientific research and diagnostic applications. This antibody is specifically designed to target and detect the ABL1 and ABL2 proteins, enabling researchers to gain valuable insights into their functions and interactions within cellular processes.

Crafted with utmost precision and utilizing cutting-edge technology, this polyclonal antibody exhibits exceptional specificity and sensitivity, ensuring accurate and reliable results. Its robust performance allows for the detection of even low-abundance ABL1 and ABL2 proteins, facilitating comprehensive analysis and investigation.

The ABL1/2 Polyclonal Antibody boasts a wide range of applications, including immunohistochemistry, immunofluorescence, western blotting, and flow cytometry. Its versatility enables researchers to explore various experimental approaches, thereby expanding the horizons of scientific exploration.

Furthermore, this antibody is manufactured under stringent quality control measures, adhering to the highest industry standards. Each batch undergoes rigorous testing to guarantee consistency and reproducibility, ensuring optimal performance and reliability across experiments.

With its exceptional specificity, sensitivity, and versatility, the ABL1/2 Polyclonal Antibody is an indispensable tool for researchers and diagnostic professionals alike. Unlock the mysteries of ABL1 and ABL2 proteins with confidence and precision, and elevate your scientific endeavors to new heights with this remarkable product.