Acetyl Histone H1 (K25) Polyclonal Antibody

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. The H1 histone family member O, oocyte specific encoded is a replication-independent histone that is a member of the histone H1 family. H1FOO contains introns, unlike most histone genes. The related mouse gene is expressed only in oocytes.

The ACETYL HISTONE H1 (K25) POLYCLONAL ANTIBODY is a highly specific and reliable tool designed for the detection and analysis of acetylated histone H1 at lysine 25. This polyclonal antibody is produced using advanced techniques, ensuring high affinity and sensitivity for the target antigen.

Histone H1 is a crucial component of chromatin structure and plays a vital role in gene regulation and DNA packaging. Acetylation of histone H1 at lysine 25 has been implicated in various biological processes, including transcriptional activation and chromatin remodeling. Therefore, the ACETYL HISTONE H1 (K25) POLYCLONAL ANTIBODY serves as an invaluable tool for researchers studying epigenetic modifications and their impact on gene expression.

This antibody exhibits exceptional specificity, as it has been extensively validated against various histone modifications and non-acetylated histone H1. Its high sensitivity allows for the detection of low abundance acetylated histone H1, enabling accurate quantification and analysis of acetylation levels in different experimental conditions.

The ACETYL HISTONE H1 (K25) POLYCLONAL ANTIBODY is suitable for a wide range of applications, including Western blotting, immunoprecipitation, chromatin immunoprecipitation (ChIP), and immunofluorescence. It is compatible with multiple species, including human, mouse, and rat, making it a versatile tool for diverse research areas.

With its exceptional performance and reliability, the ACETYL HISTONE H1 (K25) POLYCLONAL ANTIBODY is an indispensable resource for scientists and researchers investigating the intricate mechanisms of epigenetic regulation and chromatin dynamics.