AChR Alpha10 Polyclonal Antibody

Members of the ligand-gated ion channel receptor family are characterized by their fast transmitting response to neurotransmitters. Two important members of this family are the nicotinic acetylcholine and glutamate receptors, both of which are composed of five homologous subunits forming a transmembrane aqueous pore. These transmembrane receptors change conformation in response to their cognate neurotransmitter. Nicotinic acetylcholine receptors (AChRs) are found at the postsynaptic membrane of the neuromuscular junction and bind acetylcholine molecules, allowing ions to move through the pore. Glutamate receptors are found in the postsynaptic membrane of cells in the central nervous system. The activity that is generated at the synapse by the binding of acetylcholine is terminated by acetylcholinesterase, an enzyme that rapidly hydrolyzes acetylcholine. AChRα10, also known as CHRNA10, is a 450 amino acid multi-pass membrane protein expressed in inner-ear tissue, tonsil, immortalized B-cells, cultured T-cells and peripheral blood lymphocytes. AChRα10 forms a hetero-oligomeric channels in conjunction with AChRα9 and is considered an ionotropic receptor with a probable role in the modulation of auditory stimuli.

The ACHR ALPHA10 Polyclonal Antibody is a highly specialized and meticulously crafted product designed to cater to the needs of scientific research and diagnostic applications. This antibody is specifically developed to target and detect the ACHR ALPHA10 protein, a crucial component of the acetylcholine receptor.

With utmost precision and accuracy, this polyclonal antibody exhibits exceptional affinity towards the ACHR ALPHA10 protein, ensuring reliable and reproducible results. Its superior sensitivity enables the detection of even low expression levels of the ACHR ALPHA10 protein, making it an invaluable tool for various experimental and clinical investigations.

Crafted using state-of-the-art techniques and rigorous quality control measures, this antibody guarantees exceptional performance and consistency. Its high specificity ensures minimal cross-reactivity with other proteins, ensuring the utmost accuracy in experimental outcomes.

The ACHR ALPHA10 Polyclonal Antibody is supplied in a convenient and user-friendly format, allowing for easy handling and storage. Its long shelf life ensures prolonged usability, making it a cost-effective choice for laboratories and research institutions.

Whether employed in immunohistochemistry, western blotting, or other relevant techniques, this antibody promises to deliver unparalleled results, aiding in the advancement of scientific knowledge and the diagnosis of various disorders related to the acetylcholine receptor.

Choose the ACHR ALPHA10 Polyclonal Antibody for its exceptional quality, reliability, and specificity, and unlock new possibilities in your research and diagnostic endeavors.