Actinin-Alpha2/3 Polyclonal Antibody

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. ACTN2 encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for ACTN2.

The Actinin-Alpha2/3 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of Actinin-Alpha2 and Actinin-Alpha3 proteins. This antibody is produced through a rigorous process, ensuring its high affinity and sensitivity towards the target proteins.

Actinin-Alpha2 and Actinin-Alpha3 are members of the actin-binding protein family, playing crucial roles in the organization and stabilization of the cytoskeleton. They are involved in various cellular processes, including cell adhesion, migration, and contraction. The Actinin-Alpha2/3 Polyclonal Antibody enables researchers to investigate the expression, localization, and function of these proteins in a wide range of biological samples.

This antibody exhibits exceptional performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It recognizes both endogenous and recombinant Actinin-Alpha2 and Actinin-Alpha3 proteins, providing accurate and reproducible results. The Actinin-Alpha2/3 Polyclonal Antibody is compatible with multiple species, making it suitable for diverse experimental settings.

With its high specificity and sensitivity, this antibody offers researchers a valuable tool for studying Actinin-Alpha2 and Actinin-Alpha3 proteins in different biological contexts. Its reliable performance and versatility make it an indispensable asset for investigations in cell biology, developmental biology, and disease research.

The Actinin-Alpha2/3 Polyclonal Antibody is supplied in a convenient format, ensuring ease of use and storage. It is manufactured under strict quality control standards, guaranteeing batch-to-batch consistency and reliability. Researchers can trust in the quality and performance of this antibody to advance their scientific endeavors and gain deeper insights into the functions of Actinin-Alpha2 and Actinin-Alpha3 proteins.