Actinin-Alpha3 Polyclonal Antibody

ACTN3 encodes a member of the alpha-actin binding protein gene family. Actinin alpha 3 (gene/pseudogene) is primarily expressed in skeletal muscle and functions as a structural component of sarcomeric Z line. This protein is involved in crosslinking actin containing thin filaments. An allelic polymorphism in this gene results in both coding and non-coding variants; the reference genome represents the coding allele. The non-functional allele of ACTN3 is associated with elite athlete status.

The Actinin-Alpha3 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Actinin-Alpha3 protein expression in various biological samples. This antibody is produced through a rigorous process of immunization and purification, ensuring its high affinity and specificity towards Actinin-Alpha3.

With its exceptional performance, this polyclonal antibody offers researchers a reliable and accurate means to investigate the role and function of Actinin-Alpha3 in cellular processes. It is suitable for a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The Actinin-Alpha3 Polyclonal Antibody exhibits minimal cross-reactivity with other Actinin isoforms, ensuring precise and specific detection of Actinin-Alpha3 protein. Its high sensitivity allows for the detection of low levels of Actinin-Alpha3 expression, enabling researchers to explore its potential involvement in various physiological and pathological conditions.

This antibody is supplied as a liquid formulation, ready for immediate use. It has been validated for use in multiple species, including human, mouse, and rat, ensuring its versatility and applicability across different experimental models.

In summary, the Actinin-Alpha3 Polyclonal Antibody is a valuable tool for researchers seeking to investigate the expression and function of Actinin-Alpha3 protein. Its high specificity, sensitivity, and versatility make it an essential component in various research areas, including cell biology, molecular biology, and biomedical research.